Protocol Labs
PL Genesis is Protocol Labs' global builder series: hackathons surface promising projects in decentralized infrastructure, AI, and internet primitives, top teams can move into the Founders Forge accelerator, and the wider Protocol Labs ecosystem supports long-term founders. Across two completed seasons it counts 4,300+ builders, 744+ projects submitted, and $400k+ distributed in prizes; listed seasons include the Modular Worlds global hackathon (Summer 2025) and Frontiers of Collaboration (Spring 2026).
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- Active
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Web3 Foundation
Polkadot Treasury Proposals accepts rolling community-governed funding requests from its network treasury for projects that benefit the Polkadot ecosystem. Any DOT holder can submit a proposal at any time. There is no fixed funding cap or deadline. Full details and submission process are available at the Polkadot wiki.
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- Active
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Polymarket
$25k/week rewards + Builder fees, 10+ active grants
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- Active
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NEAR Foundation
Community funding platform on NEAR for public-goods and impact projects, running discovery listings and periodic quadratic-style community funding rounds.
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- Active
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Celo
Three funding pools for Celo builders: Anchor (traction-stage, $25k+), Boost (invite-only, cross-ecosystem), and Frontier (AI/agent-economy infrastructure, $25k+). 575+ applications, 120+ contracts signed, $2M distributed to date.
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- Active
- How to apply
- In rounds
National Institutes of Health
NIH's Common Fund PRIMED-AI initiative has two open RFAs for AI precision medicine: RFA-RM-27-011 (multi-use AI frameworks playbook, due 2026-10-09) and RFA-RM-27-013 (translating AI precision-medicine models into clinical use, due 2026-10-19).
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- Active
- How to apply
- In rounds
Intersect (Intersect MBO)
Project Catalyst is Cardano's community-driven, on-chain innovation funding process; the Cardano Foundation has adjusted its strategy across rounds, most recently limiting voting power and increasing focus on community-led governance in round F14.
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- Active
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Ethereum Foundation
CryptoOpen SourceIncubator
Ethereum Foundation program embedding strategic advisors with a small set of prior grantees for 12 months of sustainability planning and execution. The two-year objective is to help critical open-source teams diversify funding and reduce dependency on a single grant source.
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- Active
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Python Software Foundation
Nomination-based honorary recognition for people who have made significant contributions to the Python community. The Fellow Work Group reviews nominations each quarter. The Q3 2026 cutoff was August 20. Q4 nominations open in October and close November 20, 2026.
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- Active
- How to apply
- In rounds
Center for Civic Futures
A $20 million fund supporting real-world AI experimentation in public services and disseminating findings so other government jurisdictions can responsibly adopt the technology.
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- Active
- How to apply
- Not recorded
The Perl & Raku Foundation
A donation-funded grant initiative of The Perl & Raku Foundation supporting development of the Raku language. Proposals are reviewed on a bi-monthly cycle (call opens every two months, two-week public feedback window before committee vote).
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- Active
- How to apply
- Not recorded
Free and Open Source Software Sustainability Fund
The Open Technology Fund's Rapid Response Fund provides short-term, urgent digital security support for at-risk users facing clear, time-sensitive, state-sponsored digital emergencies. Applications are rolling.
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- Active
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Reactive Network
$3M fund backing EVM-compatible app builders via Builder Grants ($3K-$5K) and Growth Grants (up to $10K); rolling, global.
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- Active
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Responsible Technology Youth Power Fund
Annual cohort-based grants of $50,000-$100,000 for one year to youth-led and intergenerationally-led U.S. organizations working on responsible technology, with young leaders holding funding-decision roles. The 2023 and 2025 cohorts were anchored by Omidyar Network. Fund 3 applications closed October 10, 2025. The apply page says the 2026 cohort is closed and that Fund 4 applications will be announced in Fall 2026. There is no current application form.
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- Active
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- In rounds
Optimism Foundation
Retro Funding Mission rewarding developer tooling that has already delivered measurable impact to the Optimism Collective and Superchain ecosystem, distributing up to 8M OP in H1 2025. Builders join via rolling application windows with metrics-driven evaluation; the Season 8 Measurement Period 11 results list 26 rewarded projects.
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- Active
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Optimism Foundation
Retro Funding Mission rewarding onchain applications that have already delivered measurable, provable impact to the Optimism Collective and Superchain, with demonstrated significant adoption. Builders join via rolling application windows and rewards in OP are computed with metrics-driven evaluation; the Season 8 Measurement Period 11 results list 123 rewarded projects.
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- Active
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ZKsync
https://vote.zknation.io/dao/proposal/19993014537746296636853362219247192671631735482612670856590540039176244970638 [TPP-8] ZKsync Community Activation Pilot Program (2025–2026 ) allocates a total of 13.6M ZK (approximately USD $680,000 at $0.05 per token) to an RFP Pool that aims to support in-p...
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- Active
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Rocket Pool
Rocket Pool's Grants and Marketing Committee (GMC) funds grants, bounties, and retrospective awards for rETH/protocol infrastructure work, run in numbered rounds.
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- Active
- How to apply
- In rounds